In "The Cloud, the Researcher and the Repository," Leslie Carr discusses repositories and cloud computing, especially the problem of large file deposit.
Here's an excerpt from:
The solution that Tim [Brody] has come up with is to allow the researcher's desktop environment to directly use EPrints as a file system—you can 'mount' the repository as a network drive on your Windows/Mac/Linux desktop using services like WebDAV or FTP. As far as the user is concerned, they can just drag and drop a whole bunch of files from their documents folders, home directories or DVD-ROMs onto the repository disk, and EPrints will automatically deposit them into a new entry or entries. Of course, you can also do the reverse—copy documents from the repository back onto your desktop, open them directly in applications, or attach them to an email.