While AI in the context of scientific investigation has existed for decades, advances in computational technology and sensing in the physical world have created opportunities to integrate AI into science in unexpected ways, with capabilities that are rapidly accelerating. As a result, AI has been leveraged by an expanding collection of disciplines in the physical and biological sciences, as well as engineering domains. While the opportunities for AI in scientific discovery seem endless, there are numerous questions about what makes for trustworthy and reliable discovery, whether such investigation should be performed without human oversight or intervention, and how best to prioritize the research agenda and allocation of resources without magnifying disparities for individuals and nations alike.
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