Samantha Kanza, Nicholas Gibbins, and Jeremy G. Frey have published "Too Many Tags Spoil the Metadata: Investigating the Knowledge Management of Scientific Research with Semantic Web Technologies" in the Journal of Cheminformatics.
Here's an excerpt:
Previous studies of Electronic Lab Notebooks (ELNs) in academia and industry have identified semantic web technologies as a means for organising scientific documents to improve current workflows and knowledge management practices. In this paper, we present a qualitative, user-centred study of researcher requirements and practices, based on a series of discipline-specific focus groups. We developed a prototype semantic ELN to serve as a discussion aid for these focus groups, and to help us explore the technical readiness of a range of semantic web technologies. While these technologies showed potential, existing tools for semantic annotation were not well-received by our focus groups, and need to be refined before they can be used to enhance current researcher practices.